Showing posts with label Childrens. Show all posts
Showing posts with label Childrens. Show all posts

Friday, 25 November 2011

Michigan School Boards Welcome Childrens Book Author Elizabeth Hoadley for

Flushing, Michigan (PRWEB) November 10, 2011

Elizabeth A. Hoadley, CEO, The Sunshine Workshop, recently accepted invitations to speak at a number of Michigan elementary schools during National Reading Month in March 2012, including the Flushing, Flint, Bloomfield and Oakland County School Districts (Detroit/Suburban Detroit).


In a statement released yesterday, Hoadley stated, I thank them for the invitations and am delighted to accept. I am both honored and humbled to participate in these events and look forward to meeting the children."


I love to see childrens eyes light up when I read different books, like I Know I Can, or Willo, said Hoadley. The room becomes quiet when Willo the tree is cut down and becomes even more silent when he is turned into a boat and later abandoned after he is no longer useful. Theres always a burst of enthusiasm and a sigh of relief when a little boy comes to save him from a tragic end.


Typically, elementary schools throughout the United States celebrate National Reading Month with a variety of activities, including appearances by well known and highly regarded authors such as Hoadley, said The Sunshine Workshops Chief Operating Officer, Shayna Dubbin Harris. These events occur annually in most US elementary schools as part of the Department of Educations Read More Books Literacy Programs. Meeting authors such as Hoadley is one way students are encouraged to read and write books.


Since the release of I Know I Can, published in May, 2011, and the enormous positive response to it, Hoadley has accepted many opportunities to speak to a variety of audiences. Invitations are still coming in, said Dubbin Harris.


I Know I Can, written by Hoadley and illustrated by 6-year old Kailee, encourages children to believe in themselves and their natural gifts, said Dubbin Harris. Using historical figures, from Joan of Arc to Terry Fox, Hoadley poetically demonstrates that people who have achieved greatness have all had one thing in common ~ a belief in their hopes and dreams despite ridicule from others. Children often identify with the 6-Year old illustrator of the book, Kailee, when they see her painting the illustrations on YouTube I Know I Can ~ 6 Years Old and 6 Books Published.


I love how children empathize with Missy and Lizzy in I Know I Can, when they hear other kids are poking fun at Missys dreams and ridiculing what she loves most, said Hoadley. Children instinctively know right from wrong and our books help them to visualize this.


The Sunshine Workshop is busy writing and illustrating two upcoming childrens books Vivache, a story of a charming family of fish who live in the canals of Venice, each with different personality traits and The Three Graces of Aquila, a story of friendship and forgiveness inspired after witnessing earthquake reconstruction efforts in Aquila, Italy. Both books are due for release in early 2012.


The Sunshine Workshop produces childrens books, artwork, animation, musical theatre productions, and related products and has offices in the United States and Canada. Their products are available in stores, on Amazon, through their website TheSunshineWorkshop.com and their Ray of Sunshine Independent Distributors.


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Ascent Scientific Licenses Novel Dynamin Toolkits from Childrens Medical Research Institute and University of Newcastle

Bristol, UK, Sydney and Newcastle, Australia (PRWEB) March 16, 2011

Ascent Scientific together with Childrens Medical Research Institute and The University of Newcastle today announced that they have entered into a license, supply and distribution agreement for a range of small molecule dynamin inhibitors for research these are novel tools for investigating cellular processes. The agreement was facilitated by Bio-Link Australia, a life sciences commercialisation company.


Dynamin is a key protein involved in the cellular process of endocytosis, a process that involves the uptake and recycling of extracellular material by mammalian cells. Endocytic pathways are also utilised by viruses and toxins to gain entry into cells. Dynamin also participates in cell cycle progression and has shown to have critical roles in centrosome cohesion and cytokinesis.


Dynamin inhibitors have applications for researchers investigating cell signalling pathways, the cell cycle and cellular division and a range of medical conditions including cancer, infectious diseases including HIV and botulism and neurological conditions such as epilepsy.


The laboratories of Professor Adam McCluskey (University of Newcastle) and Professor Phillip Robinson (Childrens Medical Research Institute) have developed the first set of rationally designed mechanism-based pharmacological inhibitors of dynamin. These inhibitors are a range of small molecule chemicals that stop endocytosis through inhibition of the GTPase dynamin, a key protein involved in the initiation and completion of endocytosis.


McCluskey and Robinson have developed a unique portfolio of multiple classes of these small molecule dynamin inhibitors. These molecular classes selectively target different domains of dynamin providing novel research tools for understanding endocytosis biology and its role in intracellular processes and disease.


Professor McCluskey said We are very pleased that these dynamin inhibitors, which we designed and developed with the intent that they be utilized to further explore the chemical biology of dynamin and endocytosis biology, will now be available to researchers worldwide through Ascent Scientific.


Professor Robinson remarked, This palette of inhibitors provides a new means to regulate dynamins activity by independent molecules and with more than one mechanism of action, allowing scientists to more definitively assign a particular biological function to dynamin. This strategy is more powerful than relying on the use of a sole inhibitor.


Steve Roome PhD, Commercial Director for Ascent Scientific, comments "These groundbreaking tools provide a means for scientists to inhibit dynamin activity, and modulate endocytosis. Potent cell-permeable in vitro and in cell based inhibitors, together with control molecules are available individually, and in kit form providing researchers with a variety of novel ways to explore dynamin-mediated cellular processes".


The dynamin inhibitors (and their respective inactive control compounds) available from Ascent Scientific include:


Iminodyn-22

Potent, broad spectrum dynamin inhibitor. IC50 values are 450 nM and 390 nM for inhibition of dynamin I and II GTPase respectively). Binds to the GTPase domain at an allosteric site and displays uncompetitive antagonism with respect to GTP. Inhibits receptor mediated endocytosis (RME) and synaptic vesicle endocytosis (SVE) ( IC50 values are 10.7 and 108

Top U.S. Childrens Wall Art Manufacturer, Oopsy Daisy, Fine Art For Kids Launches Retail Website And Charitable Giving Campaign

San Diego, CA (PRWEB) November 22, 2011

Just in time for holiday shopping and seasonal giving, Oopsy daisy, Fine Art For Kids launches a retail e-commerce site filled with great gifts, with the added bonus of effective charitable giving. For every retail order received on the site, the childrens wall d